New efficient multicomponent reactions with C-C coupling for combinatorial application in liquid and on solid phase

被引：0
|
作者：
de Meijere, A [1 ]
Nüske, H
Es-Sayed, M
Labahn, T
Schroen, M
Bräse, S
机构：
[1] Univ Gottingen, Inst Organ & Anorgan Chem, D-37077 Gottingen, Germany
[2] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany
[3] Bayer AG, GB Pflanzenschutz, D-40789 Monheim, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1999年 / 38卷 / 24期
关键词：
combinatorial chemistry; Diels-Alder reactions; Heck reaction; multicomponent reactions; solid-phase synthesis;
D O I：
10.1002/(SICI)1521-3773(19991216)38:24<3669::AID-ANIE3669>3.0.CO;2-X
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Up to nine C-C bonds are formed selectively from up to seven components starting from an alkene, a haloarene, and a dienophile [Eq. (1)]. A comparison of liquid- and solid-phase reactions reveals a surprising superiority of the solid-phase reaction.
引用
收藏
页码：3669 / 3672
页数：4
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