Lessons from the Mycobacterium tuberculosis genome

被引：0
|
作者：
Garnier, T [1 ]
Brosch, R [1 ]
Eiglmeier, K [1 ]
Gordon, SV [1 ]
Cole, ST [1 ]
机构：
[1] Inst Pasteur, Unite Genet Mol Bacterienne, F-75724 Paris 15, France
来源：
TUBERCULOSIS IN HUMAN AND VETERINARY MEDICINE | 1999年
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D O I：
暂无
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The genome of the reference strain H37Rv of Mycobacterium tuberculosis is composed of 4,411,529 base pairs. A function has been attributed to 1,570 of the 3,924 genes identified, while a further 1,570 share certain similarities. This genome has a coding capacity greater than 90% and many repetitions. Gene sequencing has revealed the presence of 32 insertion sequences in addition to the previously described IS6110 and IS1081 sequences. It has also been shown that the MPTR and PGRS repeat sequences belong to the PE and PPE families and represent 10% of the coding capacity of the M. tuberculosis genome.
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页码：47 / 49
页数：3
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