Triheterocyclic sydnone derivatives of biological interest .1. Synthesis and antimicrobial activity of 3-aryl-4-[2-(3'-coumarylidene hydrazino)-4-thiazolyl] sydnones

被引:0
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作者
Hosmani, CK [1 ]
Mallur, SG [1 ]
Badami, BV [1 ]
机构
[1] KARNATAK UNIV,POSTGRAD DEPT STUDIES CHEM,DHARWAD 580003,KARNATAKA,INDIA
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Coumarin coupled with the thiazole ring has been introduced on the position-4-of the 3-arylsydnones via 4-bromoacetyl-3-arylsydnones in a single step method to give the title compounds (4a-l). Preliminary antimicrobial screening of all these compounds has shown antifungal activity for the methyl and halogen substituted derivatives equal to that of the standard drug.
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页码:107 / 110
页数:4
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