Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting

被引:94
|
作者
Wardelmann, E. [1 ]
Haas, R. L. [2 ]
Bovee, J. V. M. G. [3 ]
Terrier, Ph [4 ]
Lazar, A. [5 ]
Messiou, C. [6 ]
LePechoux, C. [7 ]
Hartmann, W. [1 ]
Collin, F. [8 ]
Fisher, C. [9 ]
Mechtersheimer, G. [10 ]
DeiTos, A. P. [11 ]
Stacchiotti, S. [12 ]
Jones, R. L. [13 ]
Gronchi, A. [14 ]
Bonvalot, S. [15 ]
机构
[1] Univ Hosp, Gerhard Domagk Inst Pathol, Munster, Germany
[2] Netherlands Canc Inst, Dept Radiotherapy, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands
[3] Leiden Univ, Med Ctr, Dept Pathol, Leiden, Netherlands
[4] Gustave Roussy, Dept Med Biol & Pathol, Villejuif, France
[5] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA
[6] Royal Marsden Hosp, Dept Radiol, London SW3 6JJ, England
[7] Inst Gustave Roussy, Dept Radiotherapy, Paris, France
[8] Ctr Georges Francois Leclerc, Dept Pathol, Dijon, France
[9] Royal Marsden Hosp, Sarcoma Unit, London SW3 6JJ, England
[10] Heidelberg Univ, Inst Pathol, Bergheimer Str 58, D-69115 Heidelberg, Germany
[11] Gen Hosp Treviso, Dept Oncol & Anat Pathol, Treviso, Italy
[12] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy
[13] Royal Marsden Hosp, Dept Med Oncol, London SW3 6JJ, England
[14] Fdn IRCCS Ist Nazl Tumori, Dept Surg, Milan, Italy
[15] Inst Curie, Dept Surg, Paris, France
关键词
Soft tissue sarcoma; Radiotherapy; Chemotherapy; Response evaluation; Pathology; Guideline; PREOPERATIVE HYPOFRACTIONATED RADIOTHERAPY; HIGH-RISK EXTREMITY; PHASE-I TRIAL; HIGH-GRADE; HISTOLOGIC RESPONSE; HISTOPATHOLOGIC RESPONSE; PROGNOSTIC-SIGNIFICANCE; RADIATION-THERAPY; EWINGS-SARCOMA; PLUS SORAFENIB;
D O I
10.1016/j.ejca.2015.09.021
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
At present, there is not a commonly used and generally accepted standardized approach for the pathologic evaluation of pretreated soft tissue sarcomas. Also, it is still unclear whether the cut-off for prognostic relevance is similar in the many different histological subtypes of STS. This manuscript, produced by a European Organization for Research and Treatment of Cancer - Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) endorsed task force, aims to propose standardization of the pathological examination process and the reporting of STS resection specimens after neoadjuvant radio-and/or chemotherapy. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:84 / 95
页数:12
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