Syntheses, Crystal Structures and DNA-Binding of Two Zinc(II) Complexes Constructed by 4-Methyl-1,2,3-thiadiazol-5-carboxylic Acid

Two new zinc complexes [Zn(MTC)(2)(bpp)](n) (1) and [Zn(MTC)(phen)(H2O)(2)](MTC) (2) (HMTC=4-methyl-1,2,3-thiadiazol-5-carboxylic, C4H4N2O2S; bpp=1,3-bis(4-pyridyl) propane; phen=1-10-phenanthroline) have been synthesized and characterized by single crystal X-ray diffraction, elemental analysis, IR spectra, PXRD and TG. The single crystal X-ray diffraction reveals that the complex 1 is two-dimensional network structure and crystallized in monoclinic with space group P2(1)/(c). Central Zn2+ is four-coordinated forming a distorted tetrahedron coordination geometry. The complex 2 is two-dimensional layered structure and crystallized in triclinic with space group P (1) over bar. Central Zn2+ is five-coordinated forming a distorted trigonal bipyramid coordination geometry. In addition, the interaction of complexes and ligand with EB-DNA were also studied by EtBr fluorescence probe. The interaction of complexes with DNA is stronger than ligand. CCDC: 1564691, 1; 1564890, 2.