Primary plasma cell leukemia: autologous stem cell transplant in an era of novel induction drugs

被引：23

作者：

Gowda, Lohith ^{[1
]}

Shah, Mithun ^{[2
]}

Badar, Ifra ^{[3
]}

Bashir, Qaiser ^{[3
]}

Shah, Nina ^{[4
]}

Patel, Krina ^{[5
]}

Kanagal-Shamanna, Rashmi ^{[6
]}

Mehta, Rohtesh ^{[3
]}

Weber, Donna M. ^{[5
]}

Lee, Hans C. ^{[5
]}

Manasanch, Elisabet E. ^{[5
]}

Shah, Abdul ^{[3
]}

Thomas, Sheeba K. ^{[5
]}

Parmar, Simrit ^{[3
]}

Nieto, Yago ^{[3
]}

Orlowski, Robert Z. ^{[5
]}

Champlin, Richard ^{[3
]}

Qazilbash, Muzaffar H. ^{[3
]}

机构：

[1] Yale Sch Med, Div Hematol, New Haven, CT 06511 USA

[2] Mayo Clin, Div Hematol Malignancies, Rochester, MN 55905 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplant, Houston, TX 77030 USA

[4] Univ Calif San Francisco, Div Hematol, San Francisco, CA 94143 USA

[5] Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX 77030 USA

[6] Univ Texas MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA

来源：

BONE MARROW TRANSPLANTATION | 2019年 / 54卷 / 07期

关键词：

DEXAMETHASONE; LENALIDOMIDE; MYELOMA; BORTEZOMIB; CONSOLIDATION; SURVIVAL;

D O I：

10.1038/s41409-018-0392-1

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Primary plasma cell leukemia (pPCL) is a rare and aggressive variant of multiple myeloma (MM) with poor long-term survival after cytotoxic chemotherapy. Many novel drugs have revolutionized the treatment algorithms for MM. The impact of targeted therapy, both pre- and post-autologous stem cell transplant (auto-HCT) remains an area of ongoing interest. In this study, we report outcomes post auto-HCT for pPCL and the impact of maintenance therapy posttransplant with novel agents.

引用

页码：1089 / 1093

页数：5

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