Material Processing and Design of Biodegradable Metal Matrix Composites for Biomedical Applications

被引:28
|
作者
Yang, Jingxin [1 ,2 ,3 ]
Guo, Jason L. [3 ]
Mikos, Antonios G. [3 ]
He, Chunyan [4 ]
Cheng, Guang [1 ,2 ]
机构
[1] Beijing Engn Res Ctr Smart Mech Innovat Design Se, Beijing, Peoples R China
[2] Beijing Union Univ, Robot Acad, Beijing 100101, Peoples R China
[3] Rice Univ, Dept Bioengn, 6500 Main St, Houston, TX 77030 USA
[4] Jinzhou Med Univ, Jinzhou 121000, Peoples R China
关键词
Biodegradable metal matrix composites; Processing and design; Biomedical applications; IN-VITRO BIODEGRADATION; MECHANICAL-PROPERTIES; POROUS MAGNESIUM; CORROSION BEHAVIOR; SPACE HOLDER; LACTIC ACID; ORTHOPEDIC BIOMATERIALS; ALLOYS; MICROSTRUCTURE; FOAM;
D O I
10.1007/s10439-018-2058-y
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In recent years, biodegradable metallic materials have played an important role in biomedical applications. However, as typical for the metal materials, their structure, general properties, preparation technology and biocompatibility are hard to change. Furthermore, biodegradable metals are susceptible to excessive degradation and subsequent disruption of their mechanical integrity; this phenomenon limits the utility of these biomaterials. Therefore, the use of degradable metals, as the base material to prepare metal matrix composite materials, it is an excellent alternative to solve the problems above described. Biodegradable metals can thus be successfully combined with other materials to form biodegradable metallic matrix composites for biomedical applications and functions. The present article describes the processing methods currently available to design biodegradable metal matrix composites for biomedical applications and provides an overview of the current existing biodegradable metal systems. At the end, the manuscript presents and discusses the challenges and future research directions for development of biodegradable metallic matrix composites for biomedical purposes.
引用
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页码:1229 / 1240
页数:12
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