An evaporation-based microfluidic sample concentration method

被引：91
|
作者：
Walker, GM [1 ]
Beebe, DJ [1 ]
机构：
[1] Univ Wisconsin, Dept Biomed Engn, Madison, WI 53706 USA
来源：
LAB ON A CHIP | 2002年 / 2卷 / 02期
关键词：
D O I：
10.1039/b202473j
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We present a method for sample concentration within microfluidic devices using evaporation-induced flow. Evaporation-induced flow is easy to incorporate into microfluidic designs and can be used to concentrate a wide variety of molecules. The practicality of this method was demonstrated with 0.2 mum fluorescent spheres and FITC- labeled BSA. Thirty two percent of the 0.6 muL fluorescent sphere suspension was concentrated into a well within a microfluidic device. In the same amount of time, 93% of the 0.6 muL FITC- labeled BSA solution was concentrated.
引用
收藏
页码：57 / 61
页数：5
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