Role of microRNA-34 family in cancer with particular reference to cancer angiogenesis

被引：61
|
作者：
Maroof, Hamidreza
Salajegheh, Ali
Smith, Robert Anthony
Lam, Alfred King-Yin
机构：
[1] Griffith Univ, Sch Med, Gold Coast, Qld, Australia
[2] Griffith Univ, Griffith Hlth Inst, Gold Coast, Qld, Australia
来源：
EXPERIMENTAL AND MOLECULAR PATHOLOGY | 2014年 / 97卷 / 02期
关键词：
miRNA-34; Cancer; Angiogenesis; ENDOTHELIAL-GROWTH-FACTOR; HUMAN BREAST-CANCER; PAPILLARY THYROID-CARCINOMA; ANTI-VEGF ANTIBODY; TUMOR ANGIOGENESIS; DOWN-REGULATION; LUNG-CANCER; POOR-PROGNOSIS; UP-REGULATION; EPIGENETIC INACTIVATION;
D O I：
10.1016/j.yexmp.2014.08.002
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
MicroRNA-34 is involved in pathogenesis in cancer by targeting different tumor-related genes. It could be a biomarker for predicting the prognosis of patients with cancer. In addition, miR-34 is involved in the tumor angiogenesis. Understanding the mechanism of the miR-34 in cancer and tumor angiogenesis will open horizons for development of anti-cancer and anti-angiogenesis drugs. (C) 2014 Elsevier Inn All rights reserved.
引用
收藏
页码：298 / 304
页数：7
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