A novel polymorphism in the human interleukin-13 (IL-13) promoter

被引:11
|
作者
Laundy, GJ [1 ]
Spink, CF
Keen, LJ
Wood, NAP
Bidwell, JL
机构
[1] Univ Bristol, Southmead Hosp, Div Transplantat Sci, Bristol BS10 5NB, Avon, England
[2] Univ Bristol, Dept Pathol & Microbiol, Bristol BS10 5NB, Avon, England
来源
EUROPEAN JOURNAL OF IMMUNOGENETICS | 2000年 / 27卷 / 01期
关键词
D O I
10.1046/j.1365-2370.2000.00192.x
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Using PCR-SSCP and automated nucleotide sequencing we have identified a novel single nucleotide C --> T polymorphism in the human IL-13 promoter, at position -1055 relative to the transcription start site. Allele frequency analysis in a population of normal cord blood donors indicated frequencies of 0.833 (C) and 0.167 (T).
引用
收藏
页码:53 / 54
页数:2
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