Immunohistochemical detection of p53 protein and prognosis of surgically resected non-small-cell lung cancer

被引：0
|
作者：
Quantin, X [1 ]
Pujol, JL [1 ]
Lehmann, M [1 ]
Simony, J [1 ]
Serre, I [1 ]
Michel, FB [1 ]
机构：
[1] UNIV HOSP MONTPELLIER, CHEST DEPT, ARNAUD DE VILLENEUVE HOSP, F-34295 MONTPELLIER, FRANCE
来源：
CANCER DETECTION AND PREVENTION | 1997年 / 21卷 / 05期
关键词：
immunohistochemistry; non-small-cell lung cancer; p53; prognosis; surgery;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We analyzed the survival of 89 surgically treated patients presenting non-small-cell lung cancer in regard to the accumulation of p53 protein as detected by indirect immunoperoxidase reactivity of PAb1801 anti-human p53 protein. Although the well-known factors such as stage grouping, tumor status, and nodal status were found to be prognostic determinants, the p53 protein accumulation had no effect on either univariate analysis or multivariate analysis of survival.
引用
收藏
页码：418 / 425
页数：8
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