Determination of isoniazid by flow-injection chemiluminescence analysis

被引:0
|
作者
Qu, P
Li, BX
Zhang, ZJ [1 ]
机构
[1] Shaanxi Normal Univ, Sch Chem & Mat Sci, Xian 710062, Peoples R China
[2] Shangqiu Normal Coll, Dept Chem, Shangqiu 476000, Peoples R China
关键词
D O I
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中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel flow-injection chemiluminescence ( CL) system for the determination of isoniazid was proposed. It is based on the oxidation reaction between potassium permanganate and isoniazid in the basic medium of sodium hydroxide. The system offers good selection,great sensitivity with a linear range of 0.01 similar to 5. 0 mg/L. The relative standard deviation (n = 11) is 2.5% for 0.5 mg/L isoniazid and the detection limit is 7.0 mug/L. The method has been applied to the determination of isoniazid in tablet samples with satisfactory results.
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页码:665 / 667
页数:3
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