Meta-analysis of clinical trial data is an increasingly important method in clinical research, particulary in the field of therapeutic evaluation. This method uses some specific statistical techniques which an not all available on standard packages and therefore require specific developments. This paper describes a program designed to help medical researchers perform meta-analyses of clinical trial data with dichotomous outcomes, This program includes the various statistical methods of meta-analysis and enables cumulative meta-analysis and sub-groups to be performed. A robustness index can be determined and the results obtained in table and graphic formats. Data-editing and data-manipulating facilities are also possible. Much care has been taken to make the user interface as user-friendly as possible, so that the program is within the reach of all medical researchers. (C) 1997 Elsevier Science Ireland Ltd.
机构:
Univ Southampton, Southampton Stat Sci Res Inst, Southampton SO17 1BJ, Hants, EnglandUniv Southampton, Southampton Stat Sci Res Inst, Southampton SO17 1BJ, Hants, England
Boehning, Dankmar
Mylona, Kalliopi
论文数: 0引用数: 0
h-index: 0
机构:Univ Southampton, Southampton Stat Sci Res Inst, Southampton SO17 1BJ, Hants, England
Mylona, Kalliopi
Kimber, Alan
论文数: 0引用数: 0
h-index: 0
机构:Univ Southampton, Southampton Stat Sci Res Inst, Southampton SO17 1BJ, Hants, England
机构:
Univ N Carolina, Sch Social Work, Chapel Hill, NC 27599 USA
Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA
Univ Pretoria, Pretoria, South AfricaUniv N Carolina, Sch Social Work, Chapel Hill, NC 27599 USA
Chen, Ding-Geng
Peace, Karl E.
论文数: 0引用数: 0
h-index: 0
机构:
Georgia Southern Univ, Jiann Ping Hsu Coll Publ Hlth, Statesboro, GA 30458 USAUniv N Carolina, Sch Social Work, Chapel Hill, NC 27599 USA