Dynamic kinetic resolution:: an efficient route to anti α-amino-β-hydroxy esters via Ru-SYNPHOS® catalyzed hydrogenation

被引：59
|
作者：
Mordant, C [1 ]
Dünkelmann, P [1 ]
Ratovelomanana-Vidal, V [1 ]
Genet, JP [1 ]
机构：
[1] Ecole Natl Super Chim Paris, CNRS, UMR 7573, Lab Synth Select Organ & Prod Nat, F-75231 Paris 05, France
来源：
CHEMICAL COMMUNICATIONS | 2004年 / 11期
关键词：
D O I：
10.1039/b401631a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The Ru(II)-catalyzed hydrogenation of alpha-amino-beta-keto esters as their hydrochloride salts affords preparation of the corresponding anti alpha-amino-beta-hydroxy esters under mild conditions with high diastereoselectivities and enantioselectivities via dynamic kinetic resolution.
引用
收藏
页码：1296 / 1297
页数：2
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