In randomized trials with noncompliance, causal effects cannot be identified without strong assumptions. Therefore, several authors have considered bounds on the causal effects. Applying an idea of VanderWeele (), Chiba () gave bounds on the average causal effects in randomized trials with noncompliance using the information on the randomized assignment, the treatment received and the outcome under monotonicity assumptions about covariates. But he did not consider any observed covariates. If there are some observed covariates such as age, gender, and race in a trial, we propose new bounds using the observed covariate information under some monotonicity assumptions similar to those of VanderWeele and Chiba. And we compare the three bounds in a real example.
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Univ Nebraska Med Ctr, Nebraska Med Ctr, Dept Biostat, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Nebraska Med Ctr, Dept Biostat, Omaha, NE 68198 USA
Dai, Ran
Zheng, Cheng
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Univ Nebraska Med Ctr, Nebraska Med Ctr, Dept Biostat, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Nebraska Med Ctr, Dept Biostat, Omaha, NE 68198 USA
Zheng, Cheng
Zhang, Mei-Jie
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Med Coll Wisconsin, Div Biostat, 8701 Watertown Plank Rd, Milwaukee, WI 53226 USAUniv Nebraska Med Ctr, Nebraska Med Ctr, Dept Biostat, Omaha, NE 68198 USA
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Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USAHarvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA
Chang, Chia-Rui
Song, Yue
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Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USAHarvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA
Song, Yue
Li, Fan
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Duke Univ, Dept Stat Sci, Durham, NC 27710 USAHarvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA
Li, Fan
Wang, Rui
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Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA
Harvard Pilgrim Hlth Care Inst, Dept Populat Med, Boston, MA USA
Harvard Med Sch, Boston, MA USAHarvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA