Clinical and dosimetric considerations for Y90: recommendations from an international multidisciplinary working group

被引:102
|
作者
Salem, Riad [1 ]
Padia, Siddharth A. [2 ]
Lam, Marnix [3 ]
Bell, Jon [4 ]
Chiesa, Carlo [5 ]
Fowers, Kirk [6 ]
Hamilton, Bonnie [6 ]
Herman, Joseph [7 ]
Kappadath, S. Cheenu [8 ]
Leung, Thomas [9 ]
Portelance, Lorraine [10 ]
Sze, Daniel [11 ]
Garin, Etienne [12 ]
机构
[1] Northwestern Univ, Dept Radiol, 676 N St Clair,Suite 800, Chicago, IL 60611 USA
[2] Univ Calif Los Angeles, Dept Radiol, Los Angeles, CA USA
[3] Univ Med Ctr Utrecht, Dept Radiol & Nucl Med, Utrecht, Netherlands
[4] Christie, Dept Radiol, Manchester, Lancs, England
[5] Fdn IRCCS Ist Nazl Tumouri, Dept Nucl Med, Milan, Italy
[6] BTG Int, W Conshohocken, PA USA
[7] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA
[8] Univ Texas MD Anderson Canc Ctr, Dept Imaging Phys, Houston, TX 77030 USA
[9] Hong Kong Sanat & Hosp, Comprehens Oncol Ctr, Hong Kong, Peoples R China
[10] Univ Miami, Dept Radiat Oncol, Miami, FL USA
[11] Stanford Univ, Sch Med, Dept Radiol, Palo Alto, CA 94305 USA
[12] Univ Rennes, INSERM, Ctr Lutte Canc Eugene Marquis, INRA,Inst NUMECAN Nutr Metab & Canc, F-35000 Rennes, France
关键词
Hepatocellular carcinoma; Radioembolization; Yttrium-90; Liver cancer; HEPATOCELLULAR-CARCINOMA PATIENTS; TC-99M MACROAGGREGATED ALBUMIN; SECONDARY LIVER MALIGNANCIES; ART BRACHYTHERAPY TREATMENT; GLASS MICROSPHERES; RADIATION-THERAPY; TC-99M-MACROAGGREGATED ALBUMIN; (90)YTTRIUM MICROSPHERES; RADIOEMBOLIZATION; SURVIVAL;
D O I
10.1007/s00259-019-04340-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The TheraSphere Global Dosimetry Steering Committee was formed in 2017 by BTG International to review existing data and address gaps in knowledge related to dosimetry. This committee is comprised of health care providers with diverse areas of expertise and perspectives on radiation dosimetry. The goal of these recommendations is to optimize glass microspheres radiation therapy for hepatocellular carcinoma while accounting for variables including disease presentation, tumour vascularity, liver function, and curative/palliative intent. The recommendations aim to unify glass microsphere users behind standardized dosimetry methodology that is simple, reproducible and supported by clinical data, with the overarching goal of improving clinical outcomes and advancing the knowledge of dosimetry.
引用
收藏
页码:1695 / 1704
页数:10
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