Actin dynamics: Tropomyosin provides stability

被引:115
|
作者
Cooper, JA [1 ]
机构
[1] Washington Univ, Dept Cell Biol, Sch Med, St Louis, MO 63110 USA
关键词
D O I
10.1016/S0960-9822(02)01028-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tropomyosin stabilizes actin filaments, while ADF/cofilin promotes their disassembly. These two proteins compete with each other for binding to the actin filament, providing a critical balance for actin assembly in vivo.
引用
收藏
页码:R523 / R525
页数:3
相关论文
共 50 条
  • [1] The binding dynamics of tropomyosin on actin
    Vilfan, A
    BIOPHYSICAL JOURNAL, 2001, 81 (06) : 3146 - 3155
  • [2] Tropomyosin as a Regulator of Actin Dynamics
    Khaitlina, Sofia Yu.
    INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 318, 2015, 318 : 255 - 291
  • [3] Regulation of Actin Dynamics by Tropomyosin
    Khaitlina, Sofia Yu
    Hinssen, Horst
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 568A - 568A
  • [4] Effects of tropomyosin on the dynamics of actin filament
    Khaitlina, S
    Strzelecka-Golaszewska, H
    BIOPHYSICAL JOURNAL, 2003, 84 (02) : 480A - 480A
  • [5] Cooperative effects of tropomyosin on the dynamics of the actin filament
    Khaitlina, Sofia
    Tsaplina, Olga
    Hinssen, Horst
    FEBS LETTERS, 2017, 591 (13): : 1884 - 1891
  • [6] Caldesmon and Tropomyosin Synergistically Regulate Actin Dynamics
    Huang, Renjian
    Wang, Chih-Lueh A.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 387A - 387A
  • [7] The interaction of gelsolin with tropomyosin modulates actin dynamics
    Khaitlina, Sofia
    Fitz, Helene
    Hinssen, Horst
    FEBS JOURNAL, 2013, 280 (18) : 4600 - 4611
  • [8] A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics
    Teresa T. Bonello
    Miro Janco
    Jeff Hook
    Alex Byun
    Mark Appaduray
    Irina Dedova
    Sarah Hitchcock-DeGregori
    Edna C. Hardeman
    Justine R. Stehn
    Till Böcking
    Peter W. Gunning
    Scientific Reports, 6
  • [9] A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics
    Bonello, Teresa T.
    Janco, Miro
    Hook, Jeff
    Byun, Alex
    Appaduray, Mark
    Dedova, Irina
    Hitchcock-DeGregori, Sarah
    Hardeman, Edna C.
    Stehn, Justine R.
    Boecking, Till
    Gunning, Peter W.
    SCIENTIFIC REPORTS, 2016, 6
  • [10] Jasplakinolide Reduces Actin and Tropomyosin Dynamics During Myofibrillogenesis
    Wang, Jushuo
    Fan, Yingli
    Dube, Dipak K.
    Sanger, Jean M.
    Sanger, Joseph W.
    CYTOSKELETON, 2014, 71 (09) : 513 - 529