Assessment of apparent diffusion coefficient value as prognostic factor for renal cell carcinoma aggressiveness

被引:0
|
作者
Ahmad, Medhat Ibraheem Mohammad [1 ]
Sabr, Mohammad [2 ]
Roshy, Eman [3 ]
机构
[1] Sohag Univ Hosp, Dept Radiol, Sohag, Egypt
[2] Sohag Univ Hosp, Urol Dept, Sohag, Egypt
[3] Sohag Univ Hosp, Dept Publ Hlth & Community Med, Sohag, Egypt
来源
EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE | 2019年 / 50卷 / 01期
关键词
SUBTYPE DIFFERENTIATION; WEIGHTED MRI; MASSES; BENIGN; GRADE;
D O I
10.1186/s43055-019-0038-3
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Background Assurance of prognostic elements is important for the management of renal cell carcinoma (RCC). Our goal was to check the relation between apparent diffusion coefficient (ADC) values and parameters predicting prognosis of RCC. Fifty pathologically confirmed RCC underwent diffusion-weighted (DW) MRI. ADC values were calculated using b factor (800 s/mm(2)). The correlation between ADC values and tumor size, cystic/necrotic feature, growth pattern, unenhanced T1, histological grade, clinical stage, and distant metastasis were analyzed. Results The optimal ADC threshold for prognosis of RCC appeared to be 1.4 x 10(-3) mm(2)/s. There was a significant inverse correlation between ADC values and growth pattern (R = - 0, P = 0.05), unenhanced T1(R = - 0.41, P = 0.01), cystic/necrotic feature (R = - 0.4, P = 0.01), histological grade (R = - 0.37, P = 0.02), clinical stage (r = - 0.4, P = 0.01), and distant metastasis (R = - 0.33, P = 0.04), and significant linear correlation with tumor size (R = 0.39, P < 0.02). Conclusion The performance of ADC value as a newly proposed prognostic parameter follows with the degree of tumor differentiation and that may recognize extremely aggressive RCC. RCC with low ADC values should be inspected extensively for the risk of high pathological grade, high clinical stage, and distant metastasis.
引用
收藏
页数:10
相关论文
共 50 条
  • [1] Assessment of apparent diffusion coefficient value as prognostic factor for renal cell carcinoma aggressiveness
    Medhat Ibraheem Mohammad Ahmad
    Mohammad Sabr
    Eman Roshy
    Egyptian Journal of Radiology and Nuclear Medicine, 50
  • [2] Role of Apparent Diffusion Coefficient Value and Apparent Diffusion Coefficient Ratio as Prognostic Factors for Prostate Cancer Aggressiveness
    Buss, Arvids
    Radzina, Maija
    Liepa, Mara
    Birkenfelds, Edgars
    Saule, Laura
    Miculis, Karlis
    Mikelsone, Madara
    Vjaters, Egils
    DIAGNOSTICS, 2024, 14 (21)
  • [3] Prognostic Value of Apparent Diffusion Coefficient in Oropharyngeal Carcinoma
    Sistonen, Heli J.
    Aro, Katri
    Atula, Timo
    Jouhi, Lauri
    Linden, Riikka
    Tapiovaara, Laura
    Loimu, Venla
    Markkola, Antti
    CLINICAL NEURORADIOLOGY, 2021, 31 (04) : 1037 - 1048
  • [4] Prognostic Value of Apparent Diffusion Coefficient in Oropharyngeal Carcinoma
    Heli J. Sistonen
    Katri Aro
    Timo Atula
    Lauri Jouhi
    Riikka Lindén
    Laura Tapiovaara
    Venla Loimu
    Antti Markkola
    Clinical Neuroradiology, 2021, 31 : 1037 - 1048
  • [5] Correlation of Apparent Diffusion Coefficient Value With Prognostic Parameters of Endometrioid Carcinoma
    Inoue, Chie
    Fujii, Shinya
    Kaneda, Sachi
    Fukunaga, Takeru
    Kaminou, Toshio
    Kigawa, Junzo
    Harada, Tasuku
    Ogawa, Toshihide
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2015, 41 (01) : 213 - 219
  • [6] Nasopharyngeal carcinoma: correlation of apparent diffusion coefficient value with prognostic parameters
    Razek, Ahmed Abdel Khalek Abdel
    Kamal, Elsharawey
    RADIOLOGIA MEDICA, 2013, 118 (04): : 534 - 539
  • [7] Apparent diffusion coefficient is a prognostic factor of head and neck squamous cell carcinoma treated with radiotherapy
    Masamitsu Hatakenaka
    Katsumasa Nakamura
    Hidetake Yabuuchi
    Yoshiyuki Shioyama
    Yoshio Matsuo
    Takeshi Kamitani
    Masato Yonezawa
    Takashi Yoshiura
    Torahiko Nakashima
    Mitsuru Mori
    Hiroshi Honda
    Japanese Journal of Radiology, 2014, 32 : 80 - 89
  • [8] Apparent diffusion coefficient is a prognostic factor of head and neck squamous cell carcinoma treated with radiotherapy
    Hatakenaka, Masamitsu
    Nakamura, Katsumasa
    Yabuuchi, Hidetake
    Shioyama, Yoshiyuki
    Matsuo, Yoshio
    Kamitani, Takeshi
    Yonezawa, Masato
    Yoshiura, Takashi
    Nakashima, Torahiko
    Mori, Mitsuru
    Honda, Hiroshi
    JAPANESE JOURNAL OF RADIOLOGY, 2014, 32 (02) : 80 - 89
  • [9] The prognostic value of pretreatment tumor apparent diffusion coefficient values in nasopharyngeal carcinoma
    Yan, Dan-Fang
    Zhang, Wen-Bao
    Ke, Shan-Bao
    Zhao, Feng
    Yan, Sen-Xiang
    Wang, Qi-Dong
    Teng, Li-Song
    BMC CANCER, 2017, 17
  • [10] The prognostic value of pretreatment tumor apparent diffusion coefficient values in nasopharyngeal carcinoma
    Dan-Fang Yan
    Wen-Bao Zhang
    Shan-Bao Ke
    Feng Zhao
    Sen-Xiang Yan
    Qi-Dong Wang
    Li-Song Teng
    BMC Cancer, 17