Synthesis of N-3(4-(4-chlorophenyl thiazole-2-yl)-(2-(amino)methyl)-quinzoline-4(3H)-one and their derivatives for antitubercular

被引：0
|
作者：
Pattan, Shashikant R. [1 ]
Reddy, V. V. Krishna
Manvi, F. V.
Desai, B. G.
Bhat, A. R.
机构：
[1] KLES Coll Pharm, Dept Med Chem, Belgaum 590010, India
[2] KLES Coll Pharm, Bangalore 560010, Karnataka, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2006年 / 45卷 / 07期
关键词：
mycobacterial activity; quinazolones; antitubercular; antitumour; antifungal; antithrombic; anticonvulsant;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new series of N-3[4-(4-chloroplienyl thiazole-2-yl)-2-amino methyl] quinazoline-4(3H)-one and their derivatives are synthesized. The structures of the title compounds are confirmed on the basis of IR and H-1 NMR. The compounds are screened for their antitubercular activity, using H(37)Rv strain on L J medium. All the compounds have showed moderate to promising antitubercular activity.
引用
收藏
页码：1778 / 1781
页数：4
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