New Antioxidative Secondary Metabolites from the Fruits of a Beibu Gulf Mangrove, Avicennia marina

被引：18
|
作者：
Gao, Cheng-Hai [1 ]
Yi, Xiang-Xi [2 ]
Xie, Wen-Pei [1 ,2 ]
Chen, Yin-Ning [3 ]
Xu, Ming-Ben [1 ]
Su, Zhi-Wei [1 ]
Yu, Lian [1 ]
Huang, Ri-Ming [3 ,4 ]
机构：
[1] Guangxi Acad Sci, Guangxi Key Lab Marine Environm Sci, Nanning 530007, Peoples R China
[2] Guangxi Univ Chinese Med, Sch Pharmaceut Sci, Nanning 530001, Peoples R China
[3] Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[4] Univ Bath, Dept Pharm & Pharmacol, Bath BA2 7AY, Avon, England
来源：
MARINE DRUGS | 2014年 / 12卷 / 08期
基金：
中国国家自然科学基金;
关键词：
antioxidant; Avicennia marina; caffeoyl glycoside; marinoid; phenylethyl glycoside; GLYCOSIDE;
D O I：
10.3390/md12084353
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Further chemical investigation of the fruits of the mangrove, Avicennia marina, afforded three new phenylethyl glycosides, marinoids J-L (1-3), and a new cinnamoyl glycoside, marinoid M (4). The structures of isolates were elucidated on the basis of extensive spectroscopic analysis and by comparison of the data with those of related secondary metabolites. The antioxidant activity of the isolates was evaluated using the cellular antioxidant assay (CAA), and compounds 1-4 showed antioxidant activities, with EC50 values ranging from 23.0 +/- 0.71 mu M to 247.8 +/- 2.47 mu M.
引用
收藏
页码：4353 / 4360
页数：8
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