Pd-catalyzed gem-difluoroallylation of arylboronic acids with γ,γ-difluoroallylic acetates

被引：34
|
作者：
Zhang, Bo [1 ]
Zhang, Xingang [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 06期
基金：
中国国家自然科学基金;
关键词：
ARYL BORONIC ACIDS; NUCLEOPHILIC-SUBSTITUTION; REDUCTIVE ELIMINATION; PALLADIUM; INHIBITORS; BOND; ALPHA; ALPHA-DIFLUOROKETONES; DERIVATIVES; COMPLEXES; FLUORINE;
D O I：
10.1039/c5cc08394j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly regio- and stereo-selective palladium-catalyzed gem-difluoroallylation of arylboronic acids with gamma,gamma-difluoroallylic acetates has been described. The method allows the synthesis of a variety of gem-difluoroallylated arenes with a tosyloxy group on the C=C double bond, thus providing a good opportunity for down-stream transformations.
引用
收藏
页码：1238 / 1241
页数：4
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