Recent topics of functionalized organolithiums using flow microreactor chemistry

被引:43
|
作者
Nagaki, Aiichiro [1 ]
机构
[1] Kyoto Univ, Grad Sch Engn, Dept Synthet & Biol Chem, Nishikyo Ku, Kyoto 6158510, Japan
基金
日本科学技术振兴机构;
关键词
Microreactor; Organolithium; Functional group; Residence time control; MAGNESIUM EXCHANGE-REACTION; FLASH CHEMISTRY; SPACE INTEGRATION; DIFUNCTIONAL ELECTROPHILES; PHOTOCHROMIC DIARYLETHENES; 3-COMPONENT SYNTHESIS; CHEMICAL SELECTIVITY; REACTION PATHWAYS; LOW-TEMPERATURE; RESIDENCE-TIME;
D O I
10.1016/j.tetlet.2019.07.014
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Examples in this mini-review illustrate the potential of flow microreactor chemistry in chemical science and chemical production. Flow microreactors provide a powerful method for novel transformations via functional organolithiums that cannot be achieved using a conventional macro batch reactor. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页数:8
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