IL-12/pulse IL-2 combination cytokine therapy for solid tumors: Translation from bench to bedside.

被引：0
|
作者：
Wigginton, J [1 ]
Edgerly, M [1 ]
Bates, S [1 ]
Choyke, P [1 ]
Tomaszewski, J [1 ]
Wiltrout, R [1 ]
Janik, J [1 ]
机构：
[1] NCI, NIH, Bethesda, MD 20892 USA
来源：
CLINICAL IMMUNOLOGY | 2002年 / 103卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
309
引用
收藏
页码：S102 / S102
页数：1
相关论文
共 50 条
  • [1] IL-12/IL-2 combination cytokine therapy for solid tumours: translation from bench to bedside
    Wigginton, JM
    Wiltrout, RH
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2002, 2 (05) : 513 - 524
  • [2] IL-2 and IL-12 generated cytotoxicity against pediatric solid tumors.
    DeSantes, K
    White, C
    Elder, M
    Cowan, M
    BLOOD, 1997, 90 (10) : 1226 - 1226
  • [3] The application of IL-12 to cytokine therapy and gene therapy for tumors
    Nishimura, T
    Watanabe, K
    Yahata, T
    Uede, T
    Saiki, I
    Herrmann, SH
    Kobayashi, M
    Habu, S
    INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 1996, 795 : 375 - 378
  • [4] A phase I investigation of dose-intensive intravenous IL-12/pulse IL-2 in adults with advanced solid tumors
    Wigginton, J
    Donovan, C
    Choyke, P
    Wiltrout, R
    Janik, J
    JOURNAL OF IMMUNOTHERAPY, 2003, 26 (06): : S42 - S43
  • [5] Distinct cytokine production and killer activity of NK cells derived with IL-2, IL-15 or the combination of IL-12 and IL-18
    Lauwerys, BR
    Garot, N
    Renauld, JC
    Houssiau, FA
    ARTHRITIS AND RHEUMATISM, 1999, 42 (09): : S93 - S93
  • [6] IFN-γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy
    Wigginton, JM
    Gruys, E
    Geiselhart, L
    Subleski, J
    Komschlies, KL
    Park, JW
    Wiltrout, TA
    Nagashima, K
    Back, TC
    Wiltrout, RH
    JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (01): : 51 - 62
  • [7] IMMUNOGENICITY OF A NYVAC/SIV VACCINE IN COMBINATION WITH IL-12 AND IL-2 IN RHESUS MACAQUES
    BENSON, J
    CHOUGNET, C
    TARTAGLIA, J
    SHEARER, G
    PAOLETTI, E
    GALLO, R
    FRANCHINI, G
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1995, 11 : S147 - S147
  • [8] Improved antitumour immunity in murine neuroblastoma using a combination of IL-2 and IL-12
    Siapati, KE
    Barker, S
    Kinnon, C
    Michalski, A
    Anderson, R
    Brickell, P
    Thrasher, AJ
    Hart, SL
    BRITISH JOURNAL OF CANCER, 2003, 88 (10) : 1641 - 1648
  • [9] Improved antitumour immunity in murine neuroblastoma using a combination of IL-2 and IL-12
    K E Siapati
    S Barker
    C Kinnon
    A Michalski
    R Anderson
    P Brickell
    A J Thrasher
    S L Hart
    British Journal of Cancer, 2003, 88 : 1641 - 1648
  • [10] Cytokine expression by murine NK cells in response to IL-12, IL-18 or the combination of IL-12 and IL-18
    Chakir, H
    Lemay, AM
    Webb, JR
    FASEB JOURNAL, 2001, 15 (04): : A361 - A361
12345