A novel and efficient method for the synthesis of α-aminonitriles by the reaction of aminals with trimethylsilyl cyanide catalyzed by iodine

被引：1

作者：

Saidi, M. R. ^{[1
]}

Azizi, N. ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Tehran, Iran

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2004年 / 1卷 / 02期

关键词：

trimethylsilyl cyanide; carbonyl compounds; iodine; iminium salt; aminal;

D O I：

10.1007/BF03246106

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iodine, was found to be a practical and novel catalyst for the reaction of aminal and trimethylsilyl cyanide under mild and neutral reaction condition to afford the corresponding alpha-aminonitriles in high yields and short reaction times. Trimethylsilyl iodide derived in situ from elemental iodine and trimethylsillyl cyanide catalyzed this conversion.

引用

页码：136 / 140

页数：5

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