A Cross-sectional Survey Assessing Carriage of Streptococcus pneumoniae in a Healthy Population in Xinjiang Uygur Autonomous Region of China

被引:4
|
作者
Xie Na [1 ,2 ,3 ]
Chen Zhao Yun [4 ]
Chen Tao [3 ]
Zhu Bing Qing [2 ]
Xu Li [2 ]
Gao Yuan [2 ]
Zhang Ai Yu [2 ]
Zhao Pan [2 ]
Liu Ji Wen [1 ]
Shao Zhu Jun [2 ,5 ]
机构
[1] Xinjiang Med Univ, Dept Publ Hlth, Urumqi 830054, Xinjiang, Peoples R China
[2] Chinese Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Natl Inst Communicable Dis Control & Prevent, Beijing 102206, Peoples R China
[3] Ctr Dis Control & Prevent Xinjiang Uygur Autonomo, Urumqi 830011, Xinjiang, Peoples R China
[4] Xinjiang Med Univ, Affiliated Hosp 1, Med Lab Ctr, Urumqi 830054, Xinjiang, Peoples R China
[5] Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou 310058, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Cross-sectional survey; Streptococcus pneumoniae carriage; Real-time PCR; Xinjiang; China;
D O I
10.3967/bes2018.029
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The carriage rate and serotype distribution of Streptococcus pneumoniae (S. pneumoniae) in a healthy population in China remains unclear. In this study, we collected the oropharyngeal swabs from 513 individuals in Xinjiang, China. Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S. pneumoniae carriage. The total carriage rate of S. pneumoniae was 70.4% (361/513). The most prevalent serotypes were 19B/F, 18B/C, 5, and 6A/B. The highest carriage rate of S. pneumoniae was noted in children aged 6-10 years (88.6%), which merits further attention. The co-colonization rate of two or more S. pneumoniae serotypes was 79.8% (264/331). This study aimed to investigate the baseline pneumococcal carriage rate among healthy individuals in China to improve our understanding of the epidemiology of S. pneumoniae.
引用
收藏
页码:233 / +
页数:6
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