Functionalized-Carbon Black as a Conductive Matrix for Nickel Sulfide Nanospheres and Its Application to Non-Enzymatic Glucose Sensor

The imbalance level of glucose in blood incites diabetes mellitus and it considers as a major health problem for humans. Hence, the researchers have been interested to develop non-enzymatic glucose sensors using inexpensive materials and simple synthesis route formaterial preparation. By this way, here, we report a simple and economical electrochemical method to synthesis the functionalized carbon black/nickel sulfide (f-CB/NiS) nanohybrids for non-enzymatic glucose sensor. The inexpensive and superconductive carbon black (CB) act as the best alternative conducting support than the other carbonaceous materials. Additionally, the functionalized surface of CB allows the incorporation of NiS nanospheres and improves the electrochemical performance of the NiS. The formation and structural changes of the as-preparedmaterials were evaluated by suitable spectrometry techniques. Moreover, the electrocatalytic ability of the synthesized f-CB/NiS nanohybrids was assessed using cyclic voltammetry and amperometric techniques. Our proposed sensor demonstrated an improved electrocatalytic activity toward glucose, which gives two linear concentration ranges 0.125 to 268 mu M and 268 to 1781 mu M with the lowest LOD 22 nM. In addition, our proposed non-enzymatic sensor shows the appreciable sensitivity 1223 mu AmM-1 cm(-2). The real-time utilization of the prospective sensor was evaluated successfully in biological samples such as human blood serum and urine. (C) 2018 The Electrochemical Society.