Cell Biology: Size Scaling of Mitotic Spindles

被引：2

作者：

Mitchison, T. J. ^{[1
]}

机构：

[1] Harvard Med Sch, Dept Syst Biol, Boston, MA 02115 USA

来源：

CURRENT BIOLOGY | 2020年 / 30卷 / 24期

关键词：

CYTOPLASMIC VOLUME; LENGTH; TPX2; PATHWAY;

D O I：

10.1016/j.cub.2020.09.047

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An investigation of how mitotic spindle size scales with cell size in early zebrafish embryos reveals fundamental principles of spindle organization. Spindle size depends primarily on microtubule number, which is regulated by a reaction-diffusion system when cells are large, and by signals from the plasma membrane when they are small.

引用

页码：R1476 / R1478

页数：3

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