Glioblastoma stem cell HISTArionics

被引：4
|
作者：
Natarajan, Siva Kumar [1 ]
Venneti, Sriram [1 ,2 ]
机构：
[1] Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Chad Carr Pediat Brain Tumor Ctr, Med Sch, 3520E MSRB 1,1150 W Med Ctr Dr, Ann Arbor, MI 48109 USA
来源：
CELL STEM CELL | 2022年 / 29卷 / 11期
关键词：
CANCER;
D O I：
10.1016/j.stem.2022.10.004
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Glioblastomas are lethal malignancies that possess a rapidly evolving microenvironment containing necrotic/ hypoxic areas, aberrant microvasculature, and glioblastoma stem cells (GSCs) that promote tumor growth, recurrence, and treatment resistance. Chen et al. find that GSCs drive integrated epigenetic and metabolic control of angiogenesis via histamine and propose antihistamines as potential therapies.
引用
收藏
页码：1509 / 1510
页数：3
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