Obliterating atherosclerosis of the vessels of the lower extremities, which is characteristic of most elderly people, athletes after injuries, soldiers after injuries, leads to significant changes in the condition of the limbs and, as a result, requires operative and medical treatment. A unified approach to assessing the patient's current condition and existing technologies are unable to quickly respond to changes in the patient's condition due to the lack of feedback inherent in cyber-physical systems and virtual tools based on them. This restrains the development of new technologies for the rehabilitation of patients. The conducted research made it possible to state that cyber-physical systems, where a person plays the role of the object and subject of research, are effective for the rehabilitation of such patients. For the rehabilitation of patients with obliterating atherosclerosis of the vessels of the limbs, a virtual device has been developed based on the LabVIEW software and hardware platform, which combines the functions of an electrocardiograph - to determine the heart rate - and an electromyostimulator - for muscle enhancement of arterial blood flow, taking into account the heart rate. Since the device allows you to scan the work of the heart, when the frequency of its work changes, the device monitors these changes and its output signals to the electrodes attached to the muscles at the exact moment of the passage of each current wave of blood circulation, which helps to improve the patency of blood vessels and achieve a rehabilitation effect in patients with obliterating atherosclerosis of the vessels of the limbs. The conducted research made it possible to state that cyber-physical systems, where a person plays the role of the object and subject of research, are effective for the rehabilitation of such patients.