A case with life-threatening interstitial pneumonia associated with bucillamine treatment

被引：3
|
作者：
Ogiwara, Yuiko [1 ]
Mochizuki, Hideaki [1 ]
Morioka, Takehiko [2 ]
Sugihara, Takahiko [3 ]
Makino, Fumihiko [1 ]
Takahashi, Hideki [1 ]
机构：
[1] Tokyo Metropolitan Geriatr Hosp, Div Resp Med, Itabashi Ku, Tokyo 1770015, Japan
[2] Tokyo Metropolitan Geriatr Hosp, Div Hematol, Itabashi Ku, Tokyo 1770015, Japan
[3] Tokyo Metropolitan Geriatr Hosp, Div Med & Rheumatol, Itabashi Ku, Tokyo 1770015, Japan
来源：
MODERN RHEUMATOLOGY | 2008年 / 18卷 / 05期
关键词：
Bucillamine; Elderly; Interstitial pneumonia; Lung injury; Rheumatoid arthritis;
D O I：
10.1007/s10165-008-0083-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a case of bucillamine-induced interstitial pneumonia accompanied by severe hypoxemia in an 83-year-old woman who had rheumatoid arthritis. Respiratory failure worsened even after withdrawal of bucillamine and administration of high-dose corticosteroids, and mechanical ventilation was required. A review of 15 cases with bucillamine-induced pulmonary injury suggests that advanced age may be associated with the development of severe interstitial pneumonia. Bucillamine can cause corticosteroid-resistant and life-threatening lung injury, especially in the elderly.
引用
收藏
页码：522 / 525
页数：4
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