Ionic liquids as mobile phase additives for separation of nucleotides in high-performance liquid chromatography

被引：0
|
作者：
Zhang, WZ [1 ]
He, LJ [1 ]
Liu, X [1 ]
Jiang, SX [1 ]
机构：
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Gansu, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2004年 / 22卷 / 06期
关键词：
ionic liquid; 1-alkyl-3-methylimidazolium; nucleotide; high-performance liquid chromatography;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Ionic liquids are a type of salts that are liquid at low temperature ( < 100degreesC). Because of their some special properties, they have been widely used as new "green solvents" for many chemical reactions and liquid-liquid extraction in the past several years. In this paper, a new method for the separation of nucleotides is developed and the essential feature of the method is that 1-alkyl-3-methylimidazolium salts are used as mobile phase additives, resulting in a baseline separation of nucleotides without need of gradient elution and need of organic solvent addition as currently used in RP-HPLC. This study shows the potential application of ionic liquids as mobile phase additives in reversed-phase liquid chromatography.
引用
收藏
页码：549 / 552
页数：4
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