A Phase I/II Study of the Combination of Panobinostat and Carfilzomib in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM): Final Analysis of Second Dose Expansion

被引：0
|
作者：
Berdeja, Jesus G. [1 ,2 ]
Gregory, Tara B. [1 ,3 ]
Faber, Edward [1 ,4 ]
Matous, Jeffrey [1 ,3 ]
Hart, Lowell [1 ,5 ]
Mace, Joseph R. [1 ,6 ]
Arrowsmith, Edward R. [1 ,7 ]
Flinn, Ian W. [1 ,2 ]
机构：
[1] Sarah Cannon Res Inst, Nashville, TN USA
[2] Tennessee Oncol PLLC, Nashville, TN USA
[3] Colorado Blood Canc Inst, Denver, CO USA
[4] Oncol Hematol Care Inc, Cincinnati, OH USA
[5] Florida Canc Specialists, Ft Myers, FL USA
[6] Florida Canc Specialists, St Petersburg, FL USA
[7] Tennessee Oncol PLLC, Chattanooga, TN USA
来源：
BLOOD | 2016年 / 128卷 / 22期
关键词：
D O I：
10.1182/blood.V128.22.4530.4530
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4530
引用
收藏
页数：6
相关论文
共 50 条
  • [1] A phase I/II study of the combination of panobinostat and carfilzomib in patients with relapsed or relapsed/refractory multiple myeloma: Final analysis of second dose-expansion cohort
    Berdeja, Jesus G.
    Gregory, Tara K.
    Faber, Edward A.
    Hart, Lowell L.
    Mace, Joseph R.
    Arrowsmith, Edward R.
    Flinn, Ian W.
    Matous, Jeffrey V.
    AMERICAN JOURNAL OF HEMATOLOGY, 2021, 96 (04) : 428 - 435
  • [2] Phase I/II study of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma
    Berdeja, Jesus G.
    Hart, Lowell L.
    Mace, Joseph R.
    Arrowsmith, Edward R.
    Essell, James H.
    Owera, Rami S.
    Hainsworth, John D.
    Flinn, Ian W.
    HAEMATOLOGICA, 2015, 100 (05) : 670 - 676
  • [3] A phase I/II study of the combination of panobinostat (PAN) and carfilzomib (CFZ) in patients (pts) with relapsed or relapsed/refractory multiple myeloma (MM).
    Berdeja, Jesus G.
    Gregory, Tara K.
    Matous, Jeffrey
    Hart, Lowell L.
    Owera, Rami
    Mace, Joseph Ronald
    Essell, James H.
    Flinn, Ian
    Faber, Edward Anthony
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [4] A Phase I/II Study of the Combination of Panobinostat (PAN) and Carfilzomib (CFZ) in Patients (pts) with Relapsed or Relapsed/Refractory Multiple Myeloma (MM): Comparison of Two Expansion Cohorts
    Berdeja, Jesus G.
    Gregory, Tara B.
    Faber, Edward A.
    Matous, Jeffrey V.
    Hart, Lowell L.
    Mace, Joseph R.
    Peyton, James D.
    Essell, James H.
    Arrowsmith, Edward R.
    Flinn, Ian W.
    BLOOD, 2015, 126 (23)
  • [5] Phase I/II Study of Panobinostat and Carfilzomib in Patients (pts) with Relapsed or Refractory Multiple Myeloma (MM), Interim Phase I Safety Analysis
    Berdeja, Jesus G.
    Hart, Lowell
    Lamar, Ruth
    Murphy, Patrick
    Morgan, Susan
    Flinn, Ian W.
    BLOOD, 2012, 120 (21)
  • [6] Phase I/Ib study of carfilzomib and panobinostat with or without dexamethasone in patients with relapsed/refractory multiple myeloma
    Manasanch, Elisabet E.
    Shah, Jatin J.
    Lee, Hans C.
    Weber, Donna M.
    Thomas, Sheeba K.
    Amini, Behrang
    Olsem, Jasper
    Crumpton, Brandon
    Morphey, Ashley
    Berkova, Zuzana
    Feng, Lei
    Orlowski, Robert Z.
    HAEMATOLOGICA, 2020, 105 (05) : E242 - E245
  • [7] Phase I Study of the Combination of Carfilzomib and Panobinostat for Patients with Relapsed and Refractory Myeloma: A Multiple Myeloma Research Consortium (MMRC) Clinical Trial
    Kaufman, Jonathan L.
    Zimmerman, Todd
    Rosenbaum, Cara A.
    Nooka, Ajay K.
    Heffner, Leonard T.
    Harvey, R. Donald
    Gleason, Charise
    Lewis, Colleen
    Sharp, Cathy
    Barron, Kenisha W.
    Lonial, Sagar
    BLOOD, 2014, 124 (21)
  • [8] PHASE I STUDY OF THE COMBINATION OF CARFILZOMIB AND PANOBINOSTAT FOR PATIENTS WITH RELAPSED AND REFRACTORY MYELOMA: A MULTICENTER MMRC CLINICAL TRIAL
    Kaufman, J.
    Zimmerman, T.
    Jakubowiak, A.
    Rosenbaum, C.
    Lewis, C.
    Harvey, D.
    Nooka, A.
    Heffner, L.
    Lonial, Sagar
    HAEMATOLOGICA, 2013, 98 : 322 - 323
  • [9] A Phase I Study of Ixazomib in Combination with Panobinostat and Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma
    Reu, Frederic J.
    Valent, Jason
    Malek, Ehsan
    Sobecks, Ronald M.
    Faiman, Beth M.
    Hamilton, Kimberly
    Elberson, Jamie
    Fada, Sherry
    Liu, Hien K.
    Samaras, Christy
    Smith, Mitchell R.
    BLOOD, 2015, 126 (23)
  • [10] Phase II Study of Infusional Carfilzomib in Patients with Relapsed or Refractory Multiple Myeloma
    Lendvai, Nikoletta
    Landau, Heather
    Lesokhin, Alexander
    Tsakos, Ioanna
    Koehne, Guenther
    Chung, David
    Devlin, Sean
    Hassoun, Hani
    Giralt, Sergio A.
    BLOOD, 2012, 120 (21)
12345