THE ANTITHROMBOTIC AND BLEEDING EFFECTS OF DABIGATRAN, A DIRECT THROMBIN INHIBITOR, AS COMPARED TO ENOXAPARIN, HEPARIN AND WARFARIN IN RATS

被引:0
|
作者
Van Ryn, J. [1 ]
Kuritsch, I. [1 ]
Kink-Eiband, M. [1 ]
Priepke, H. [1 ]
Wienen, W. [1 ]
机构
[1] Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany
来源
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1011
引用
收藏
页码:407 / 407
页数:1
相关论文
共 50 条
  • [1] Comparison of the antithrombotic and bleeding effects of the direct thrombin inhibitor, dabigatran, with enoxaparin, heparin and warfarin in rats
    van Ryn, J.
    Kuritsch, I
    Kink-Eiband, M.
    Priepke, H.
    Wienen, W.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 756 - 757
  • [2] ANTITHROMBOTIC AND BLEEDING EFFECTS OF A NEW SYNTHETIC DIRECT THROMBIN INHIBITOR AND OF STANDARD HEPARIN IN THE RABBIT
    CADROY, Y
    CARANOBE, C
    BERNAT, A
    MAFFRAND, JP
    SIE, P
    BONEU, B
    THROMBOSIS AND HAEMOSTASIS, 1987, 58 (02) : 764 - 767
  • [3] Comparison of antithrombotic and haemorrhagic effects of edoxaban, an oral direct factor Xa inhibitor, with warfarin and enoxaparin in rats
    Morishima, Yoshiyuki
    Honda, Yuko
    Kamisato, Chikako
    Tsuji, Naoki
    Kita, Akemi
    Edo, Naoko
    Shibano, Toshiro
    THROMBOSIS RESEARCH, 2012, 130 (03) : 514 - 519
  • [4] The combination of apixaban, a direct factor Xa inhibitor, with heparin or enoxaparin in rabbits elicits additive antithrombotic effects, with low bleeding
    Wong, P.
    Watson, C.
    Knabb, R.
    Crain, E.
    EUROPEAN HEART JOURNAL, 2008, 29 : 133 - 134
  • [5] Effects of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate, on thrombus formation and bleeding time in rats
    Wienen, Wolfgang
    Stassen, Jean-Marie
    Priepke, Henning
    Ries, Uwe Joerg
    Hauel, Norbert
    THROMBOSIS AND HAEMOSTASIS, 2007, 98 (02) : 333 - 338
  • [6] Differential effects of the direct thrombin inhibitor dabigatran etexilate vs warfarin on platelet function
    Renda, G.
    Malatesta, G.
    Bucciarelli, V.
    Napoleone, A.
    Candelori, L.
    Van Ryn, J.
    Moretti, L.
    De Caterina, R.
    EUROPEAN HEART JOURNAL, 2012, 33 : 968 - 968
  • [7] Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat
    Elg, M
    Gustafsson, D
    Carlsson, S
    THROMBOSIS RESEARCH, 1999, 94 (03) : 187 - 197
  • [8] Dual combination of apixaban, a direct factor Xa inhibitor, with heparin or enoxaparin produced additive antithrombotic effects with low bleeding in rabbits
    Wong, Pancras C.
    Watson, Carol A.
    Crain, Earl J.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2008, 28 (06) : E68 - E68
  • [10] EFFECTS OF DABIGATRAN, A DIRECT THROMBIN INHIBITOR, AS COMPARED TO ENOXAPARIN AND THE DIRECT FACTOR XA INHIBITOR, RIVAROXABAN, ON TISSUE FACTOR-INDUCED PLATELET AGGREGATION IN HUMAN PLATELET RICH PLASMA
    van Ryn, J.
    Kink-Eiband, M.
    Hauel, N.
    Priepke, H.
    Wienen, W.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2008, 93 : 148 - 149