The Effect of Probiotics in Prevention of Necrotising Enterocolitis in Preterm Neonates in Comparison with Control Group

被引：4

作者：

Amini, Elaheh ^{[1
]}

Dalili, Hosein ^{[2
]}

Niknafs, Nikoo ^{[1
]}

Shariat, Mamak ^{[3
]}

Nakhostin, Maryam ^{[4
]}

Jedari-Attari, Saeid ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Vali Asr Hosp, Maternal Fetal & Neonatal Res Ctr, Tehran, Iran

[2] Univ Tehran Med Sci, Vali Asr Hosp, Breastfeeding Res Ctr, Tehran, Iran

[3] Univ Tehran Med Sci, Maternal Fetal & Neonatal Res Ctr, Vali Asr Hosp, Tehran, Iran

[4] Univ Tehran Med Sci, Breastfeeding Res Ctr, Vali Asr Hosp, Tehran, Iran

来源：

IRANIAN JOURNAL OF PEDIATRICS | 2017年 / 27卷 / 06期

关键词：

Probiotics; NEC; Premature Neonate; BACTERIAL-COLONIZATION; BIFIDOBACTERIUM BREVE; PREMATURE-INFANTS; INTESTINAL FLORA; LACTOBACILLUS; SUPPLEMENTATION; MICROFLORA; PREBIOTICS;

D O I：

10.5812/ijp.7663

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Background: Necrotizing enterocolitis (NEC) is a common dangerous gastrointestinal emergency in neonatology, especially in premature infants, which can cause serious problems. Objectives: This study was conducted to find out whether administration of probiotics could lead to prevention and/or treatment of NEC. Methods: 115 premature newborns weighting 750 - 1500 g or less than 32 weeks' gestation were checked daily for NEC signs and weight gain and mean day of full feed achievement was recorded. Results: The incidence of NEC and C-reactive protein (CRP) rise showed a significant difference (P = 0.02) between the two (case and control) groups, but the difference regarding mean duration of oxygen therapy, TPN, full feeding achievement, and hospitalization was not significant. Conclusions: These results showed positive effects of probiotics on preventing and treating NEC, especially NEC grade 3 in ELBW and VLBW neonates.

引用

页数：4

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