Chemical composition and antimicrobial activity of the essential oils from flowers and leaves of Grindelia integrifolia DC

被引：5
|
作者：
Nowak, Slawomira [1 ]
Lisiecki, Pawel [2 ]
Tomaszczak-Nowak, Anna [1 ]
Grudzinska, Ewa [1 ]
Olszewska, Monika Anna [1 ]
Kicel, Agnieszka [1 ]
机构：
[1] Med Univ Lodz, Dept Pharmacognosy, Lodz, Poland
[2] Med Univ Lodz, Dept Pharmaceut Microbiol & Microbiol Diagnost, Lodz, Poland
来源：
NATURAL PRODUCT RESEARCH | 2019年 / 33卷 / 10期
关键词：
Grindelia integrifolia; essential oil; GC-FID; MS; monoterpenes; sesquiterpenes; antimicrobial activity; ANTIFUNGAL ACTIVITY; ROBUSTA NUTT; ANTIBACTERIAL; SQUARROSA; ACIDS;
D O I：
10.1080/14786419.2017.1423302
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Essential oils from flowers and leaves of Grindelia integrifolia DC. were investigated for the first time in terms of chemical composition and antimicrobial activity. The GC-FID/MS analysis allowed for the identification of 58 and 72 volatiles, comprising 92.4 and 90.1% of the oils, respectively. The major components of the flower oil were alpha-pinene (34.9%) and limonene (13.1%), while myrcene (16.9%), spathulenol (12.3%), beta-eudesmol (11.9%) and limonene (10.1%) dominated among the leaf volatiles. The antimicrobial activity, evaluated against 12 selected bacteria and fungus, was found moderate, with the strongest effect of both oils observed against C. albicans (MIC = MBC: 0.63 and 0.31 mg/mL for flower and leaf oil, respectively). [GRAPHICS] .
引用
收藏
页码：1535 / 1540
页数：6
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