A novel titanium tetrahalide-mediated carbon-carbon bond-forming reaction:: Regioselective synthesis of substituted (E,Z)-1,5-dihalo-1,4-dienes

被引:36
|
作者
Kabalka, GW [1 ]
Wu, ZZ
Ju, YH
机构
[1] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA
[2] Univ Tennessee, Dept Radiol, Knoxville, TN 37996 USA
关键词
D O I
10.1021/ol026507r
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Reactions of aldehydes with 2 equiv of alkyne in the presence of TiX4 (X = Cl, Br) regioselectively generated 1,5-dihalo-1,4-dienes in moderate to good yields with high (E,Z)-stereoselectivity.
引用
收藏
页码:3415 / 3417
页数:3
相关论文
共 10 条