Hsp70 Inhibitor Could Induce Transplant Tolerance through mTORC2/Akt Pathway.

被引：0
|
作者：
Gu, G. [1 ]
Lu, T. [1 ]
Xu, N. [1 ]
Xia, Q. [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Dept Liver Surg, Shanghai, Peoples R China
来源：
AMERICAN JOURNAL OF TRANSPLANTATION | 2018年 / 18卷
关键词：
D O I：
暂无
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
A437
引用
收藏
页码：624 / 624
页数：1
相关论文
共 35 条
  • [1] Hsp70 associates with Rictor and is required for mTORC2 formation and activity
    Martin, Jheralyn
    Masri, Janine
    Bernath, Andrew
    Nishimura, Robert N.
    Gera, Joseph
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 372 (04) : 578 - 583
  • [2] Efficacy of INK128, an mTORC1/mTORC2 kinase inhibitor, in breast cancer models driven by HER2-PI3K-AKT-mTOR pathway.
    De, Pradip
    Sun, Yuliang
    Wu, Hui
    Rommel, Christian
    Liu, Yi
    Dey, Nandini
    Leyland-Jones, Brian
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [3] TESTOSTERONE COULD INDUCE CARDIAC HYPERTROPHY IN OVARIECTOMIZED SHR THROUGH THE ACTIVATION OF THE MTORC2/ATG9A
    Wang, Wenting
    Zhu, Lulu
    Chen, Jianshu
    Wang, Qiongying
    Yu, Jing
    JOURNAL OF HYPERTENSION, 2024, 42
  • [4] Allicin protects traumatic spinal cord injury through regulating the HSP70/Akt/iNOS pathway in mice
    Wang, Shunyi
    Ren, Dongliang
    MOLECULAR MEDICINE REPORTS, 2016, 14 (04) : 3086 - 3092
  • [5] RES-529: a PI3K/AKT/mTOR pathway inhibitor that dissociates the mTORC1 and mTORC2 complexes
    Weinberg, Mark A.
    ANTI-CANCER DRUGS, 2016, 27 (06) : 475 - 487
  • [6] HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis
    Seo, Seung Un
    Min, Kyoung-jin
    Woo, Seon Min
    Seo, Ji Hae
    Kwon, Taeg Kyu
    MOLECULES, 2018, 23 (11):
  • [7] OXA-01, a selective inhibitor of mTORC1/mTORC2, enhances apoptosis induced by chemotherapeutic agents through inhibition of Akt phosphorylation
    Barr, Sharon
    Russo, Suzanne
    Maresca, Paul
    Garton, Andrew
    Crew, Andrew
    Bhagwat, Shripad
    Iwata, Kenneth
    Epstein, David
    Pachter, Jonathan
    Miglarese, Mark
    CANCER RESEARCH, 2009, 69
  • [8] Geranylgeranylacetone attenuates myocardium ischemic/reperfusion injury through HSP70 and Akt/GSK-3lβ/eNOS pathway
    Zhou, Chunxia
    Bai, Jie
    Jiang, Chuan
    Ye, Lincai
    Pan, Yanjun
    Zhang, Haibo
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2017, 9 (02): : 386 - 395
  • [9] Polycystin-1 regulates cell proliferation and migration through AKT/mTORC2 pathway in a human craniosynostosis cell model
    Katsianou, Maria A.
    Papavassiliou, Kostas A.
    Gargalionis, Antonios N.
    Agrogiannis, George
    Korkolopoulou, Penelope
    Panagopoulos, Dimitrios
    Themistocleous, Marios S.
    Piperi, Christina
    Basdra, Efthimia K.
    Papavassiliou, Athanasios G.
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2022, 26 (08) : 2428 - 2437
  • [10] ITGB1 suppresses autophagy through inhibiting the mTORC2/AKT signaling pathway in H9C2 cells
    ZHOU, W. E. I. W. E. I.
    LIU, W. E. I. Z. H. E.
    ZHOU, D. I. N. G. Y. A. N.
    LI, A. I. Y. I. N. G.
    PHARMAZIE, 2022, 77 (05): : 137 - 140
1234