DETECTING SPARSE CONE ALTERNATIVES FOR GAUSSIAN RANDOM FIELDS, WITH AN APPLICATION TO fMRI

被引:4
|
作者
Taylor, Jonathan E. [1 ]
Worsley, Keith J. [2 ,3 ]
机构
[1] Stanford Univ, Dept Stat, Stanford, CA 94305 USA
[2] Univ Chicago, Chicago, IL 60637 USA
[3] McGill Univ, Dept Math & Stat, Montreal, PQ H3A 2K6, Canada
关键词
Euler characteristic; kinematic formulae; multivariate one-sided hypotheses; non-negative least squares; order-restricted inference; random fields; volumes of tubes expansion; EXCURSION SETS; UNKNOWN LOCATION; CONFIDENCE BANDS; MAXIMA; SIGNALS; GEOMETRY; LATENCY; SMOOTH; CHI(2); VOLUME;
D O I
10.5705/ss.2012-218s
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Our problem is to find a good approximation to the P-value of the maximum of a random field of test statistics for a cone alternative at each point in a sample of Gaussian random fields. These test statistics have been proposed in the neuroscience literature for the analysis of fMRI data allowing for unknown delay in the hemodynamic response. However the null distribution of the maximum of this 3D random field of test statistics, and hence the threshold used to detect brain activation, was unsolved. To find a solution, we approximate the P-value by the expected Euler characteristic (EC) of the excursion set of the test statistic random field. Our main result is the required EC density, derived using the Gaussian Kinematic Formula.
引用
收藏
页码:1629 / 1656
页数:28
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