Mathematical and computational challenges in population biology and ecosystems science

被引:275
|
作者
Levin, SA
Grenfell, B
Hastings, A
Perelson, AS
机构
[1] UNIV CAMBRIDGE, DEPT ZOOL, CAMBRIDGE CB2 3EJ, ENGLAND
[2] UNIV CALIF DAVIS, INST THEORET DYNAM, DIV ENVIRONM STUDIES, DAVIS, CA 95616 USA
[3] UNIV CALIF DAVIS, CTR POPULAT BIOL, DAVIS, CA 95616 USA
[4] LOS ALAMOS NATL LAB, LOS ALAMOS, NM 87545 USA
关键词
D O I
10.1126/science.275.5298.334
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Mathematical and computational approaches provide powerful tools in the study of problems in population biology and ecosystems science. The subject has a rich history intertwined with the development oi statistics and dynamical systems theory, but recent analytical advances, coupled with the enhanced potential of high-speed computation, have opened up new vistas and presented new challenges. Key challenges involve ways to deal with the collective dynamics of heterogeneous ensembles oi individuals, and to scale from small spatial regions to large ones. The central issues-understanding how detail at one scale makes its signature felt at other scales, and how to relate phenomena across scales-cut across scientific disciplines and go to the heart of algorithmic development of approaches to high-speed computation. Examples are given from ecology, genetics, epidemiology, and immunology.
引用
收藏
页码:334 / 343
页数:10
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