Prevalence and Predictors of Masked Inefficacy of Treatment of Arterial Hypertension During Use of Various Groups of Antihypertensive Drugs

Prevalence and predictors of masked arterial hypertension (AH) in patients receiving antihypertensive therapy (concealed treatment inefficacy - CTI) was studied on material of data base comprising 219 observations. Drugs from 5 groups were used. Prevalence of CTI AH with the use of various definitions was 8.1-17.4%. With the help of procedure of logistic regression analysis the following predictors of CTI were selected: (1) sociopsychological - high working capacity, high psychological abilities and social self feeling; (2) parameters of 24-hour BP profile - 24-hour variability, variability during working period, minimal daytime BP level, time of maximal BP. According to our data CTI is most probable during treatment with calcium antagonists and beta-adrenoblockers