Pregabalin in the treatment of postmastectomy chronic pain: Results of an open label, single-arm clinical study

被引：8
|
作者：
Kaur, Navneet [1 ]
Kumar, Ashwani [1 ]
Saxena, Ashok Kumar [2 ]
Grover, Rajesh Kumar [3 ]
机构：
[1] UCMS & GTB Hosp, Dept Surg, Delhi, India
[2] UCMS & GTB Hosp, Dept Anesthesia, Delhi, India
[3] Delhi State Canc Inst, Delhi, India
来源：
BREAST JOURNAL | 2019年 / 25卷 / 03期
关键词：
neuropathic pain; postmastectomy chronic pain; pregabalin; quality of life; BREAST-CANCER SURGERY; NEUROPATHIC PAIN; POSTOPERATIVE PAIN; MASTECTOMY; IMPACT;
D O I：
10.1111/tbj.13242
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Postmastectomy chronic pain (PMCP) is one of the important survivorship issues faced by breast cancer patients. It is a chronic pain which persists for more than 3 months after mastectomy or quadrantectomy and is considered to be neuropathic in nature. An open label, single-arm, prospective study was conducted to evaluate the efficacy of Pregabalin in relieving clinically significant PMCP (pain score >= 3 on visual analogue scale). Pregabalin brought about significant reductions in pain (visual analogue scale [VAS] Scores; baseline 5.50 +/- 1.197, end of 1 month 2.40 +/- 1.430, end of 2 months 2.10 +/- 1.370) and significant improvement in quality of life.
引用
收藏
页码：465 / 468
页数：4
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