Extremely low frequency (ELF) pulsed-gradient magnetic fields inhibit malignant tumour growth at different biological levels

被引:35
|
作者
Zhang, XC
Zhang, HS [1 ]
Zheng, CY
Li, CY
Zhang, XS
Xiong, W
机构
[1] Wuhan Univ, Dept Phys, Biomed Phys Unit, Wuhan 430072, Peoples R China
[2] Wuhan Univ, Coll Life Sci, Wuhan 430072, Peoples R China
[3] Wuhan Univ, Sch Business, Wuhan 430072, Peoples R China
[4] Huazhong Univ Sci & Technol, Inst Syst Engn, Wuhan 430074, Peoples R China
基金
中国国家自然科学基金;
关键词
extremely low frequency (ELF) pulsed-gradient magnetic field; malignant tumour; inhibitory; biological levels;
D O I
10.1006/cbir.2002.0883
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Extremely low frequency (ELF) pulsed-gradient magnetic field (with the maximum intensity of 0.6-2.0 T, gradient of 10-100 T . M-1, pulse width of 20-200 ms and frequency of 0.16-1.34 Hz treatment of mice can inhibit murine malignant tumour growth, as seen from analyses at different hierarchical levels, from organism, organ, to tissue, and down to cell and macromolecules. Such magnetic fields induce apoptosis of cancer cells, and arrest neoangiogenesis, preventing a supply developing to the tumour. The growth of sarcomas might be amenable to such new method of treatment. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:599 / 603
页数:5
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