Optical Properties of Active Pharmaceutical Ingredients in Terahertz Region

被引:0
|
作者
Aytekin, Yusuf Samet [1 ]
Kokturk, Mustafa [2 ]
Zaczek, Adam [3 ]
Korter, Timothy M. [3 ]
Heilweil, Edwin J. [4 ]
Esenturk, Okan [1 ]
机构
[1] Middle East Tech Univ, Dept Chem, TR-06100 Ankara, Turkey
[2] Nobel Pharmaceut Res & Dev Ctr, TR-81100 Duzce, Turkey
[3] Syracuse Univ, Dept Chem, Syracuse, NY 13244 USA
[4] Natl Inst Stand & Technol, Engn Phys Div, Gaithersburg, MD 20899 USA
关键词
D O I
10.1109/irmmw-thz.2019.8874394
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
In this study Terahertz (THz) spectra of several commonly used active pharmaceutical ingredients are reported. Results showed that all the API's had unique bands associated with the structures allowing to analyse both qualitatively and quantitatively. The liq. nitrogen temperature and solid state and gas phase theoretical analysis of meloxicam have also been carried out. In addition, the transparency of the drug packaging materials like plastic blisters, cartons were checked to see the technique's ability for in situ nondestructive penetrating analysis.
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页数:2
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