Facile synthesis of a reduction-responsive amphiphilic triblock polymer via a selective thiol-disulfide exchange reaction

被引:16
|
作者
Liu, Xiangyu [1 ]
He, Jingwen [1 ]
Hu, Ding [1 ]
Niu, Yile [1 ]
Xia, Xinnian [1 ]
Lu, Yanbing [1 ]
机构
[1] Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China
来源
RSC ADVANCES | 2014年 / 4卷 / 90期
关键词
CROSS-LINKED MICELLES; GLUTATHIONE; LIGHT; NANOPARTICLES;
D O I
10.1039/c4ra07792j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A reduction-responsive amphiphilic triblock copolymer mPEG-b-PDS-b-mPEG was synthesized via polycondensation between a dithiol and dipyridyl disulfide, followed by a selective thiol-disulfide exchange reaction. The reduction-triggered release of Nile Red by DTT was further demonstrated using fluorescence spectroscopy.
引用
收藏
页码:48897 / 48900
页数:4
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