Salvage surgery after head and neck squamous cell carcinoma treated with bioradiotherapy

被引：7
|
作者：
Rovira, Aleix [1 ]
Tornero, Jordi [1 ]
Oliva, Marc [2 ]
Taberna, Miren [2 ]
Montal, Robert [2 ]
Nogues, Julio [1 ]
Farre, Anna [1 ]
Lares, Henry [1 ]
Navarro, Valenti [3 ]
Mari, Antoni [4 ]
Maria Vinals, Joan
Lozano, Alicia [5 ,6 ]
Mesia, Ricard [2 ]
Manos, Manel [1 ]
机构：
[1] Univ Barcelona, Bellvitge Univ Hosp, Dept Otorhinolaryngol, Barcelona, Spain
[2] Univ Barcelona, Catalan Inst Oncol, Dept Med Oncol, Barcelona, Spain
[3] Hosp Duran & Reynalds, Catalan Inst Oncol, Stat Unit, Barcelona, Spain
[4] Univ Barcelona, Bellvitge Univ Hosp, Dept Maxillofacial Surg, Barcelona, Spain
[5] Univ Barcelona, Bellvitge Univ Hosp, Dept Plast & Reconstruct Surg, Barcelona, Spain
[6] Univ Barcelona, Catalan Inst Oncol, Hosp Duran & Reynalds, Dept Radiotherapy, Barcelona, Spain
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2017年 / 39卷 / 01期
关键词：
salvage surgery; head and neck squamous cell carcinoma; bioradiotherapy; cetuximab; head and neck cancer; ORGAN-PRESERVATION THERAPY; POSTOPERATIVE COMPLICATIONS; TOTAL LARYNGECTOMY; PHARYNGOCUTANEOUS FISTULA; SURGICAL COMPLICATIONS; PLUS CETUXIMAB; CANCER; RECURRENT; CHEMORADIOTHERAPY; RADIOTHERAPY;
D O I：
10.1002/hed.24549
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Background. The purpose of this study was to describe the results and complications of primary site salvage surgery after head and neck squamous cell carcinoma (HNSCC) treated with bioradiotherapy. Methods. We conducted a retrospective chart review of 268 patients treated with bioradiotherapy between March 2006 and December 2013 at the Hospital Universitari de Bellvitge-ICO. Results. Fifty-nine patients developed local recurrence or had residual disease with a 1-year and 3-year overall survival of 47% and 15.4%, respectively. Salvage surgery was feasible in 22 patients (37.3%). There were 16 complications in these 22 patients (72.7%), 11 (50%) of which were major. Bilateral neck dissection was identified as a risk factor for complications. Conclusion. Salvage surgery after bioradiotherapy is associated with a high rate of complications. Neck dissection seems to be related to an increased rate of complications with no survival improvement. (C) 2016 Wiley Periodicals, Inc.
引用
收藏
页码：116 / 121
页数：6
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