Point-of-care HIV RNA testing and immediate antiretroviral therapy initiation in young adults seeking out-patient care in Kenya

被引：4
|
作者：
Sanders, Eduard J. [1 ,2 ]
Chirro, Oscar [1 ]
Oduor, Clifford [1 ]
Mangi, Juma [3 ]
Wahome, Elizabeth [1 ]
Price, Matthew A. [4 ]
Gelderblom, Hubert C. [1 ]
van der Elst, Elisabeth M. [1 ]
Graham, Susan M. [1 ,5 ]
机构：
[1] Kenya Govt Med Res Ctr, Wellcome Trust Res Programme, POB 230, Kilifi, Kenya
[2] Univ Oxford, Nuffield Dept Med, Oxford, England
[3] Malindi Subcty Hosp, Malindi, Kenya
[4] Int Aids Vaccine Initiat, New York, NY USA
[5] Univ Washington, Seattle, WA 98195 USA
来源：
AIDS | 2019年 / 33卷 / 05期
基金：
英国惠康基金;
关键词：
INFECTION; MALARIA; AFRICA; COMMON;
D O I：
10.1097/QAD.0000000000002110
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We evaluated outcomes of an HIV-1-testing intervention using rapid HIV tests followed by point-of-care Xpert Qual testing for HIV-1 RNA. Of 706 young urgent-care seeking participants evaluated, 24 (3.4%) had chronic HIV (antibody-positive), 3 (0.4%) acute HIV-1 (Qual-positive, antibody-negative), and 3 (0.4%) early HIV-1 infection (Qual-positive, antibody-discordant). Overall, 21 (70.0%) diagnosed patients started antiretroviral therapy after a median of 4 days (range 0-71). HIV-1 RNA testing led to an increase in confirmed diagnoses by 25%.
引用
收藏
页码：923 / 925
页数：3
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