Objectives: The aim of this study was to determine the interaction of four polyacid-modified resin composites with aqueous lactic acid solutions, and to compare changes with those for a glass-ionomer cement and a conventional resin composite. Methods: For each material, namely Compoglass F, Dyract AP, Hytac and Ana Compomer, plus AquaCem (glass-ionomer cement) and Pekafil (conventional composite resin), five cylindrical specimens of 4 mm diameter x 6 mm height were prepared and weighed. They were stored individually in 2.0 cm(3) of 0.02 mol l(-1) lactic acid solution for 1 week then the pH was determined and the specimens reweighed. The lactic acid solution was replenished, and the specimens were stored for a further week, after which the pH and specimen weights were again measured. This was repeated at 1 week intervals until the specimens were 6 weeks old. Differences were analysed by ANOVA followed by Newman-Keuls post hoc analysis. Results: All four polyacid-modified composites increased the pH of the solutions at all time intervals by at least 0.26 pH units (significant to at least p < 0.01). This effect was similar to that of the glass-ionomer (but significantly less, p < 0.05) while significantly greater (p < 0.05) than that for the composite, Pekafil, which, by contrast, had no effect on pH. The observed rise in pH reduced significantly over time (ANOVA, p < 0.05). After 1 week, all pH changes were accompanied by net reductions in specimen mass, indicating susceptibility to acid erosion. Hytac was significantly more resistant to this erosion than the other materials; conversely, it had the least effect on solution pH. Significance: These results show that polyacid-modified resin composites neutralise lactic acid in vitro but suffer erosion in the process. (C) 1999 Academy of Dental Materials. Published by Elsevier Science Ltd. All rights reserved.