Cytotoxic diterpenoids from Pteris ensiformis

被引：11

作者：

Shi, Yu-Sheng ^{[1
]}

Zhang, Yan ^{[2
]}

Hu, Wen-Zhong ^{[1
]}

Zhang, Li-Hong ^{[2
]}

Chen, Xi ^{[3
,4
,5
,6
]}

Zhang, Ning ^{[2
]}

Li, Guang ^{[5
,6
]}

Tan, Li-Yan ^{[7
]}

机构：

[1] Dalian Nationalities Univ, Coll Life Sci, Key Lab Biotechnol & Bioresources Utilizat, State Ethn Affairs Commiss,Minist Educ, Dalian 116600, Peoples R China

[2] Heilongjiang Univ Chinese Med, Jiamusi Coll, Jiamusi 154007, Peoples R China

[3] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China

[4] Peking Union Med Coll, Beijing 100193, Peoples R China

[5] Chinese Acad Med Sci, Inst Med Plant Dev, Jinghong 666100, Peoples R China

[6] Peking Union Med Coll, Yunnan Branch, Jinghong 666100, Peoples R China

[7] Jiamusi Univ, Affiliated Hosp 1, Dept Endocrinol, Jiamusi 154003, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2017年 / 19卷 / 02期

关键词：

Pteris ensiformi; Pteridaceae; ent-kaurane diterpenoid; cytotoxicity; ent-kaurane-6; 16-diol-3-one; ENT-KAURANE DITERPENOIDS; SEMIPINNATA; PTERIDACEAE; DERIVATIVES; MULTIFIDA; FERNS; ACIDS;

D O I：

10.1080/10286020.2016.1274307

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemistry investigation on Pteris ensiformis led to the isolation of a new ent-kaurane diterpenoid, ent-kaurane-6,16-diol-3-one (1), along with five known diterpenoids (2-6) and three known sesquiterpenes (7-9). Their structures were established by means of spectroscopic methods. The ethanol extract and the isolated compounds (1-9) were evaluated for their antitumor activity against three cancer cell lines.

引用

页码：188 / 193

页数：6

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