Methylene acetals as protecting groups - An improved preparation method

被引：15

作者：

Guiso, M

Procaccio, C

Fizzano, MR

Piccioni, F

机构：

[1] Dipartimento di Chimica, Università La Sapienza, I-00185 Roma

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(97)00882-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile method to protect vic diols, 1,3 diols and other hydroxyl functions as methylene acetals is achieved by treating the relative substances with POCl3 or SOCl2 in DMSO. The good yields obtained, the good solubility of maw organic compounds in DMSO and the easy hydrolysis of the 1,3,5-trioxaepane derivatives prepared from trans vic diols make useful this protecting method. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：4291 / 4294

页数：4

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