THE CLINICAL BURDEN AND PREDICTORS OF SEQUELAE FOLLOWING INVASIVE MENINGOCOCCAL DISEASE IN AUSTRALIAN CHILDREN

被引：25

作者：

Wang, Bing ^{[1
,2
]}

Clarke, Michelle ^{[2
]}

Thomas, Natalie ^{[2
]}

Howell, Stuart ^{[3
]}

Afzali, Hossein Haji Ali ^{[4
]}

Marshall, Helen ^{[2
,5
,6
]}

机构：

[1] Univ Adelaide, Sch Populat Hlth Paediat & Reprod Hlth, Adelaide, SA 5005, Australia

[2] Womens & Childrens Hosp, Vaccinol & Immunol Res Trials Unit VIRTU, Adelaide, SA 5006, Australia

[3] Univ Adelaide, Data Management & Anal Ctr, Discipline Publ Hlth, Adelaide, SA 5005, Australia

[4] Univ Adelaide, Discipline Publ Hlth, Adelaide, SA 5005, Australia

[5] Univ Adelaide, Robinson Inst, Adelaide, SA 5005, Australia

[6] Univ Adelaide, Sch Paediat & Reprod Hlth, Adelaide, SA 5005, Australia

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2014年 / 33卷 / 03期

关键词：

invasive meningococcal disease; sequelae; OUTCOMES;

D O I：

10.1097/INF.0000000000000043

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Of 109 children admitted to a tertiary paediatric hospital with a diagnosis of invasive meningococcal disease from 2000-2011, 37.6% (n = 41) developed sequelae; for serogroup B, 41.3% developed sequelae. Independent predictors of sequelae included: fever 39 degrees C on hospital presentation [odds ratio (OR): 4.5; P = 0.012] and a diagnosis of septicemia with meningitis compared with septicemia alone (OR: 15.5; P < 0.001) and meningitis alone (OR: 7.8; P = 0.002).

引用

页码：316 / 318

页数：3

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